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Evaluate Every affected individual's hazard just before prescribing and monitor all patients routinely for the development of such behaviors or circumstances.CYP450 3A4 Conversation: The concomitant use with CYP450 3A4 inhibitors (or discontinuation of CYP450 3A4 inducers) might cause a fatal overdose of oxycodone.Neonatal Opioid Withdrawal Syndrom